https://www.cabidigitallibrary.org/doi/full/10.5555/20210243378
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Effects of ganoderma extraction and eight-week endurance exercises on plasma values neurotrophic factors based on brain and nerve growth in men with Parkinson's.
Abstract
A quasi-experimental clinical trial was conducted to investigate the effect of Ganoderma lucidum extract and eight weeks of endurance training on plasma levels of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in men with Parkinson's disease. Out of 86 male patients with Parkinson's disease in Ardabil University of Medical Sciences in Iran, 24 subjects were purposefully selected and randomly divided into four groups of six (1 placebo, 2 exercises and placebo, 3 supplements and 4 exercises). The exercise program was conducted for 8 weeks, three sessions per week under the supervision of a physiologist, sports physician and neurologist with an intensity of 50 to 65% of the maximum heart rate in the gym. Blood samples of subjects were collected 24 hours before the first session and 24 hours after the last session of exercise and after spending about 10 hours of fasting at night. The results showed that there was a significant difference for plasma levels of NGF and BDNF in exercise, supplement and supplement-exercise groups. Also, the study of intergroup changes showed a significant difference in post-test compared to pre-test.
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55
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Effects of ganoderma extraction and eight-week endurance exercises on plasma values neurotrophic factors based on brain and nerve growth in men with Parkinson's.
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